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9 Probiotic-Powered Products That Support your Skin and Microbiome

From luxurious serums to barrier-strengthening oils, transform your routine with these seven products.
Sophia Connolly

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Photo: Shutterstock

“It is important to maintain and preserve the skin barrier to keep the good things in and bad things out,” says Melissa Kanchanapoomi Levin, M.D., a consulting dermatologist for Strivectin, says. “The skin barrier and the microbiome act like a shield that protects the body against aggressions. There is a balanced interplay between our skin and resident and/or transient bacterial populations.”

To maintain and preserve the skin barrier, many have turned to probiotic skincare, which bring together cutting-edge science and nature’s wisdom. From microbiome-supporting foundations to hydration-packed overnight creams, these products go beyond surface care to fortify the skin barrier, restore balance and enhance natural glow.

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Esse Skincare Foundation

This hybrid Foundation ($65) seamlessly blends the benefits of high-performance makeup with the advanced microbiome skincare for which Esse is known. It offers a flawless, natural coverage while simultaneously nurturing the skin. Enriched with live probiotics, the foundation also enhances complexion while supporting a healthy skin microbiome, and the probiotics strengthen the skin’s natural barrier, promoting a more radiant appearance over time.

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Georgette Klinger Probiotic Serum

Georgette Klinger’s Probiotic Serum ($56) is made with a blend of watermelon, quinoa, grapeseed, and prickly pear extracts and hyaluronic acid. The complementary ingredients improve the skin’s natural moisturizing factor and help it achieve a healthy ecosystem. The serum is designed to improve the skin’s ability to hydrate from within, while also strengthening the natural microbial shield.

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PAUME Probiotic Hand Balm

With notes of crisp lemon, herbaceous rosemary, and aromatic cedar, PAUME’s Probiotic Hand Balm ($24) is a practical and much-needed tool for the arid winter months ahead. It contains Hydersia G2, which delivers skin-nourishing vitamins and increases moisture. It is also infused with natural probiotics, which restore the skin’s natural microbiome, and plant-based active ingredients.

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Lumene Hydration Recharge Overnight Cream

The nurturing Hydration Recharge Overnight Cream ($21.99) works overnight to release hydration deep into the skin. Prebiotic Finnish oat xylitol and postbiotic fermented Nordic oat help to reinforce moisture barrier, ensuring both instant and long-lasting hydration in the morning. Oat is converted by fermentation processes into simpler, bio-available substances, while organic nordic birch sap and Lumene’s exclusive hydra-technology support continuous hydration throughout the night.

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StriVectin Super-B Barrier Strengthening Oil

Super-B Barrier Strengthening Oil ($72) is a dual-focused treatment oil from StriVectin that supports the microbiome and skin barrier to target visible signs of aging and dry, dull skin. Luxurious yet lightweight, this clinically proven oil calms and nourishes the skin for an even, glowing complexion.

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Kaibae Gut/Skin Resistance

Kailbae offers a base layer for skin immunity with Gut/Skin Resistance ($58), a dietary supplement made with a blend of wild plant polyphenols with rich antioxidant benefits. Phytoceramides, prebiotics, and probiotics are shown to improve gut microbiome and skin barrier function. Improving the gut microbiome health with probiotics and prebiotics improves nutrient absorption and makes nutrients available to the whole body.

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La Flore Discovery Kit

This three-step regimen sampler from La Flore utilizes the natural power of live probiotics to nourish and restore skin’s vibrance. The Discovery Kit ($99) is ideal for those looking to reduce redness, inflammation and improve hydration. The kit includes Enzymatic Cleanser, Live Probiotic Concentrated Serum, Daily Defense Moisturizer, and Longevity Oil.

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Circadia Pre & Post Biotic Nourishing Mask

Elevate with your treatment with Circadia’s Pre and Post Biotic Nourishing Mask ($65), a powerhouse formula designed to balance the skin’s microbiome while offering protection against blue light damage. Key ingredients like royal tea provide antioxidant and blemish-reducing benefits, while the brand’s proprietary CM-Glucan Forte strengthens the skin barrier, offering soothing relief for irritated skin. The mask supports hydration and healing, while also regulating circadian rhythms in keratincytes for balanced, glowing skin.

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Skin 1004 Probio-Cica Bakuchiol Eye Cream

Skin 1004’s Probio-Cica Bakuchiol Eye Cream ($21) is a gentle formula that combines fermented centella and bakuchiol to stimulate collagen production and visibly reduce fine lines and wrinkles. With a rich cream texture, the cream absorbs quickly into delicate skin around the eye area, providing deep moisture. It is clinically proven to reduce fine lines and wrinkles in two weeks.

About The Author
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Sophia is an intern for Well Defined. She is passionate about journalism and has focused on writing stories covering adoption, sports, and other topics as a staff writer and copy editor for her high school yearbook staff. She has achieved several high school journalism awards for her writing and has aspirations for a successful professional writing career.